In February there was an abundance of funding raised by companies in the Biotech and Biopharma space. Within this blog, Invenia Group Consultant Katie Davis dives into key findings, and the companies raising these funds. You can subscribe to monthly biotech funding updates over on LinkedIn to keep up to date with the ever-growing biotech market.
Key Stats:
Total Funding: $27.27B
October funding: $9.34B
November funding: $6.42B
December funding: $11.50B
Grant Funding
October
100,000 BioCytics Inc (NC, USA) via the Human Applications Lab is focused on bringing personalized oncology treatments to the market.
275,000 EpiVario, Inc. (PA, USA) develops novel compounds to treat memory-related psychiatric disorders at the source of the disease.
300,000 Luminary Therapeutics, Inc (MN, USA) is a clinical stage CAR-T therapy company with a novel allogeneic manufacturing platform where their CAR and or TCR development utilizes gamma delta cells.
500,000 EydisBio, Inc. (NC, USA) is the operator of a biotech platform dedicated to developing medical solutions for cancer and arthritis.
500,000 Moleculera Biosciences (OK, USA) a precision medicine company focused on immune-mediated neuropsychiatric, cardiovascular, long-COVID, and neurodegenerative disorders
525,000 HemoSonics (VA, USA) is a medical device company bringing innovative in vitro diagnostics to market to characterize hemostasis.
1,000,000 Axovia Therapeutics (United Kingdom) develops transformative therapies targeting critical aspects of ciliopathies.
1,000,000 Amphix Bio (IL, USA) is a preclinical company developing a new class of supramolecular therapeutics that instruct cells to initiate regenerative processes and restore function lost from injury, disease, or aging.
1,150,000 PopVax (India) is a full-stack biotechnology company developing novel mRNA vaccines and therapeutics.
1,558,805 Okomera (France) is a biotech start-up that accelerates access to improved, precision-based cancer therapies.
1,600,000 The Jackson Laboratory (ME,USA) conducts mammalian genetics research offering scientific services and resources to laboratories and students.
1,600,000 Early is Good (IN, USA) mission is to develop highly accurate and non-invasive multi-omic molecular testing solutions for complex diseases like cancer. The company has developed a Multi-omic Integration Platform that combines detection of DNA, RNA, protein and metabolite targets into a single assay.
1,632,726 Atomo Diagnostics (Australia) design and manufactures blood-based, lateral flow rapid diagnostic test (RDT) devices.
1,800,000 Asymmetrex®, LLC (MA, USA) develops stem cell medicine technology. They developed kinetic stem cell (KSC) counting, the first technology for accurate determination of the differential stem cell count of preparations for use in stem cell transplantation medicine and pre-clinical drug evaluations.
1,800,000 RevOpsis Therapeutics (IL, USA) is a next-generation biopharmaceutical company that is trailblazing a new era in multispecific antibody discovery and development to unlock transformative treatments for complex disease.
1,800,000 Previse (MD, USA) is a life sciences company focused on the development and commercialization of diagnostic tests for cancer prevention.
1,963,343 Proteotype Diagnostics (United Kingdom) providing cross-sectional snapshots, like a CT scan for your blood. They want to impact both primary and secondary care pathways. Their mission is to light the way in which cancer is diagnosed, treated and monitored.
2,000,000 Brixton Biosciences (MA, USA) is a clinical-stage life sciences company that develops therapies for chronic and acute pain.
2,163,980 BioVersys AG (Switzerland) develops novel antibacterial products to combat serious life-threatening infections caused by MDR bacteria.
2,250,000 Visolis (CA, USA) uses synthetic biology to manufacture high performance materials. Their systems approach integrates innovations in synthetic biology, chemical catalysis and process scale-up to enable new bio-based manufacturing platforms.
2,339,363 BIOINTAXIS (Spain) is a biotechnology company that develops and offers advance technology products for neurodegenerative diseases.
2,500,000 Selonterra, Inc. (CA, USA) is a biopharmaceutical company that works on Alzheimer’s and Parkinson’s disease therapies and diagnostics.
2,600,000 TME Pharma (Germany) is a clinical-stage company focusing on developing novel therapies for treatment of the most aggressive cancers.
3,000,000 Xylo Bio (CO, USA) is a drug development company that focuses on next-generation psychedelics.
3,000,000 Gravidas Diagnostics, Inc. (CA, USA) is developing a rapid PoC test to identify pregnant women at risk of developing severe or life-threatening preeclampsia.
3,000,000 Glaucus (NY, USA) develops novel nanotech solutions for the future of at-home diagnostics. Our revolutionary biosensing technology empowers people to diagnose various health conditions and diseases at-home, with high accuracy.
3,000,000 General Proximity (CA, USA) aims to create a therapeutic to an undruggable target, which may be able to target multiple cancers in women.
3,000,000 Nura Health (CA, USA) is a molecular diagnostics company whose mission is to advance women’s health through the development and delivery of novel practice-changing non-invasive tests and precision medicine tools.
3,000,000 University of North Carolina at Chapel Hill aims to treat migraines by targeting the lymphatic system and unique female biology that increases migraine susceptibility.
3,300,000 Allyx Therapeutics (CT, USA) is a clinical-stage biotechnology company that develops therapies to reverse neurodegeneration.
3,300,000 Vanderbilt University Medical Center (TN, USA) aims to develop an at-home medication to mitigate the health risks of preterm labour.
3,400,000 Washington University in St. Louis (MO, USA) aims to develop a blood test that decodes pain and tracks symptoms to create treatments for conditions like endometriosis.
3,500,000 Celmatix Therapeutics (NY, USA) is a preclinical-stage women’s health biotech focused on advancing groundbreaking therapeutics for women’s health. With its growing pipeline of innovative drug programs including an AMHR2 agonist program focused on ovarian aging, an oral FSH for infertility, and a JNK inhibitor program for endometriosis.
5,000,000 J. Craig Venter Institute (MD, USA) is a non-profit organization engaged in the research of genomics.
5,000,000 NRG Therapeutics (United Kingdom) is a drug discovery company focussed on therapeutic approaches that will restore mitochondrial function.
8,000,000 Integral Molecular (PA, USA) is a research-driven biotechnology company creating innovative technologies and a pipeline of therapeutic antibodies
9,000,000 Beth Israel Deaconess Medical Center (MA, USA) aims to develop a non-invasive imaging biomarker to evaluate brain disorders in women.
10,000,000 Daré Bioscience, Inc. ® (CA, USA) is a clinical-stage biopharma company committed to the advancement of innovative products for women’s health, they have eight potentially first-in-class women’s health products in development.
10,000,000 Aspira Women’s Health (CT, USA) is transforming women’s gynaecological health with the discovery, development, and commercialization of innovative testing options for women of all races and ethnicities, starting with ovarian cancer.
10,000,000 Gameto (NY, USA) use advanced cellular engineering to reprogram hiPSCs into engineered ovarian and endometrial cell lines. Their proprietary transcription factor combinations enable these cells to mimic native functions—producing and responding to all hormones—to deliver better patient solutions.
10,000,000 University of Iowa aims to develop an ovarian cancer treatment using personalized nanoparticles and a woman’s own immune system.
11,000,000 Tuskegee University (AL, USA) received up to $11M from NHGRI to establish a Genomic Research Center. The center will enhance public understanding of genomics in disease prevention and treatment while driving workforce development, community outreach, and ethics initiatives to build the next generation of genomic health scientists in rural Alabama.
17,000,000 CanSino Biologics Inc.康希诺生物 (China) focuses on the R&D, manufacturing, and commercialization of vaccine products for human use.
17,500,000 Resilience (CA, USA) is a biomanufacturing company that provides access to complex medicines and protects biopharmaceutical supply chains.
20,000,000 Varro (NY, USA) develops technologies to detect airborne pathogens and prevent disease transmission.
60,000,000 Every Cure (PA, USA) is a non-profit organization dedicated to unlocking the full potential of every existing medicine to treat every disease possible.
Unknown RedHill Biopharma Ltd. (Israel) specializes primarily in gastrointestinal and infectious diseases within the realm of specialty biopharmaceuticals.
Unknown AN2 Therapeutics (CA, USA) focuses on modern biomedical and drug development expertise to provide transformational medicines.
Unknown Virica Biotech (Canada) is a biotechnology company that addresses the unmet needs in production and development to positively change human health.
Unknown ATCC (VA, USA) is a non-profit organization which collects, stores, and distributes standard reference microorganisms, cell lines and other materials for research and development.
Unknown Rise Therapeutics (MD, USA) is focused on developing targeted immunological-based biologics using a unique and proprietary oral delivery platform.
grant financing and equity investment 11,500,000 ALTRATECH LIMITED (Ireland) has developed and patented a fundamentally novel process to detect and quantify DNA, RNA, Antibody, and Antigen molecular targets.
November
120,000 4M Therapeutics Inc. (NJ, USA) develops therapies for central nervous system (CNS) disorders with blockbuster potential.
250,000 TC BioPharm (United Kingdom) develops safer, cheaper, consistent, and durable CAR-T drugs for hematological and solid tumors.
1,256,114 Centauri Therapeutics Limited (United Kingdom) is a biotechnology company focused on the discovery and development of treatments for life-threatening diseases.
1,268,887 GLOX Therapeutics Ltd. (United Kingdom) creates precision antibiotics using engineered protein bacteriocins.
1,400,000 Bexion Pharmaceuticals (KY, USA) is a biotech company focused on developing and commercializing innovative cancer treatments.
1,897,344 Microplate Dx Limited (United Kingdom) develops diagnostic technology to reduce fatalities caused by drug-resistant infections.
1,953,865 VitroScan (Netherlands) develops certified predictive ex vivo 3D tumour testing services for reliable treatment response prediction and improved patient stratification in clinical trials.
1,960,249 Phlox Therapeutics (Netherlands) specializes in developing gene therapies to alleviate and cure cardiomyopathies.
2,000,000 Dovetail Genomics (CA, USA) uses proximity ligation technology to provide insights into genomic structures and variations.
2,000,000 Onc.AI (CA, USA) specializes in clinical oncology, genomics, proteomics, and radiomics.
2,110,000 Roswell Park Comprehensive Cancer Center (NY, USA) provides a multidisciplinary approach for scientists and clinicians researching oncology.
2,700,000 Integral Molecular (PA, USA) is a research-driven biotechnology company creating innovative technologies and a pipeline of therapeutic antibodies.
2,700,000 Novel Microdevices (MD, USA) is a medical device start-up developing a handheld point-of-care device for molecular diagnostics.
4,200,000 CND Life Sciences (AZ, USA) develops an evidence-based tool to help confirm a diagnosis of synucleinopathy.
4,750,000 Eisbach Bio GmbH (Germany) is a biotechnology company creating new drugs that target molecular vulnerabilities in cancer genomes.
4,822,152 Relevium Medical (Ireland) is a biopharmaceutical company offering medicines for osteoarthritis.
14,000,000 Barricade Therapeutics (TX, USA) integrates complex molecule synthesis, chemistry, and molecular pharmacology with targeted therapeutic approaches in cancer biology.
19,500,000 Sparian Biosciences (NY, USA) is an early-stage CNS-focused biopharmaceutical firm developing transformative medicines targeting the brain through innovative science and novel drug discovery.
Unknown NeuroDex (MA, USA) develops diagnostics, theranostics, prognostics, and pharmacodynamic analysis tools.
December
840,760 Orikine Bio (Spain) is a pioneering biotech company specializing in tailored cytokines for the treatment of immune-mediated disorders.
1,400,000 Weill Cornell Medicine (NY, USA) is an academic medical institution offering healthcare services.
1,700,000 Orphagen Pharmaceuticals (CA, USA) is a drug discovery company.
3,500,000 Baylor College of Medicine Medicine (TX, USA) is a health sciences university that advances education, healthcare, and community service locally and globally.
3,600,000 VitriVax (CO, USA) is a biotech startup developing a vaccine formulation platform.
5,000,000 Humanetics Corporation (MN, USA) is a clinical-stage pharmaceutical company focused on proprietary drugs for medical countermeasures, radiation modulators, and inflammatory lung diseases.
7,300,000 Akava Therapeutics, Inc. (IL, USA) develops small molecule therapeutics that inhibit protein aggregation, enzymes, and cancer for neurodegenerative diseases.
7,300,000 Basilea Pharmaceutica (Switzerland) is a commercial-stage biopharmaceutical company.
7,900,000 GangaGen Biotechnologies (India) is a clinical-stage biotechnology company focused on developing novel therapeutic proteins.
12,000,000 Antheia, Inc. (CA, USA) is a synthetic biology company developing next-generation plant-inspired medicines.
35,500,000 TigaTx (MA, USA) develops an IgA therapeutic monoclonal antibody platform for treating solid tumors.
40,000,000 Aramis Biotechnologies (Canada) specializes in developing novel vaccines in plants.
Unknown Keltic Pharma Therapeutics (United Kingdom) enhances drug discovery through innovative scientific research.
Unknown Aphios Corporation (MA, USA) is a green biotechnology company developing technology platforms for drug discovery, delivery, and safety.
Unknown LIPUM AB (Sweden) operates as a biotechnology company offering anti-inflammatory drugs.
Additional funding announcements
October
1,306,520 Monument Therapeutics (United Kingdom) develops products to treat serious diseases of the central nervous system.
3,000,000 Ancilia Biosciences (United States) is harnessing the natural power of CRISPR to develop a new class of bacterial therapies and products for a range of applications.
5,100,000 Starget Pharma (Israel) develops a novel somatostatin-based targeted therapy platform.
5,414,596 Confocal.nl (Netherlands) improves the microscopy experience of researchers by offering confocal imaging solutions that minimize phototoxicity.
14,000,000 Sunbird Bio (Singapore) is a leader in protein-based diagnostic tests, accurately detecting Alzheimer’s disease with a simple blood draw.
14,700,000 Model Medicines (CA, USA) uses human expertise and AI to accelerate the development of life-changing drugs at scale.
45,000,000 Leal Therapeutics (MA, USA) develops novel therapeutics for patients with central nervous system (CNS) disorders.
65,000,000 EvolveImmune Therapeutics (CT, USA) creates first-in-category cancer medicines with superior, long-term outcomes compared to current therapies.
82,000,000 Be Biopharma (MA, USA) develops a class of B cells as medicines.
November
1,743,097 Clair Scientific (Denmark) develops the Nebula, a fully automated microscope based on innovative new imaging technology.
6,317,399 Cytomos (United Kingdom) provides integrated, predictive analytics systems for intelligent bioprocessing in biopharma.
9,064,837 Aurealis Therapeutics (Finland) is a clinical-stage company developing multi-target cell and gene therapies for complex diseases such as chronic wounds, cancers, and inflammation.
15,000,000 ReCode Therapeutics (TX, USA) is a genetic medicines company specializing in mRNA and gene correction therapeutics.
20,400,000 Secretome Therapeutics (TX, USA) specializes in neonatal mesenchymal stem cells for disease treatment.
70,000,000 Jupiter Bioventures (DE, USA) is a biotechnology venture foundry that builds science-driven startups at scale.
Unknown Khondrion (Netherlands) is a clinical-stage biopharmaceutical company developing therapies for primary mitochondrial disease (PMD).
Unknown BioLink (China) provides process solutions for the life science industry, focusing on the R&D and manufacturing of equipment for biological product production.
December
678,891 Amped PCR (United Kingdom) produces PCR reagents that outperform industry gold standards while costing a fraction of the price.
954,213 AmplifiDx (CA, USA) provides a molecular point-of-care device combining visual appeal with ease of use, low cost, and high performance.
1,531,239 Newcells Biotech Ltd (United Kingdom) specializes in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types.
4,078,858 PeptiSystems AB (Sweden) manufactures instruments for solid-phase synthesis of peptide and oligonucleotide therapeutics.
5,200,000 Orthogon Therapeutics (MA, USA) develops antiviral drugs for immune-suppressed patients.
10,000,000 Bluenote (CA, USA) uses AI to create systems that meet security standards like HIPAA, GDPR, SOC2, CLIA, and CAP.
12,000,000 Orange Health Labs (Bangalore, Karnataka, India) is a full-stack diagnostic lab offering on-demand pathology testing services.
22,500,000 Indapta Therapeutics (CA, USA) develops allogeneic g-NK cells for combination therapies with monoclonal antibodies and immune cell engagers.
30,000,000 bit.bio (Cambridgeshire, UK) specializes in coding human cells for health using computational biology principles.
45,000,000 Institut Pasteur de Dakar (Senegal) is a biomedical research center developing testing kits for infectious diseases.
60,000,000 Earli Inc. (CA, USA) develops genetic constructs for early cancer detection and targeted therapy.
@75,000,000 nChroma Bio (MA, USA) develops targeted in vivo delivery systems and best-in-class cargo.
Corporate round
October
2,500,000 Novus Diagnostics (Ireland) are developing a revolutionary sample-to-answer sepsis diagnostic device.
20,000,000 AviadoBio (United Kingdom) transform the lives of people living with neurodegenerative disorders by developing and delivering transformative gene therapies
November
Unknown Arcalis (Japan) specializes in manufacturing processes for messenger RNA pharmaceuticals.
December
2,157,497 Umecrine Cognition AB (Sweden) develops drugs for central nervous system disorders caused by endogenous CNS-active steroids.
11,000,000 Pepromene Bio (CA, USA) is a clinical-stage biotech startup dedicated to developing innovative therapeutics for cancer and immunological illnesses.
Unknown Eikonizo Therapeutics (MA, USA) is producing brain-penetrant small compounds and using in vivo target engagement approaches to accelerate therapeutic discovery.
December equity crowdfunding
2,100,000 Epi One (NY, USA) aims to take early cancer diagnosis to the next level by leveraging a novel epigenetic biomarker platform.
Private equity
October
421,000,000 Treeline Biosciences (CT, USA) is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.
December
Unknown VIVEbiotech (Spain) is a GMP Contract Development and Manufacturing Organization (CDMO) specialized in Lentiviral vectors.
Post-IPO Equity
October
326,173 Arch Biopartners (Canada) acquires and develops products and technology for sale to pharmaceutical and industrial companies.
990,774 Asep Medical Holdings Inc. (Canada) develops a diagnostic assay for the early and rapid diagnosis of sepsis.
1,500,000 XORTX Therapeutics Inc. (Canada) is a biopharmaceutical company focused on developing innovative therapies to treat progressive kidney disease.
2,000,000 Calidi Biotherapeutics (CA, USA) is a clinical-stage biotechnology company developing immunotherapies for cancer.
2,440,000 MAIA Biotechnology, Inc. (IL, USA) is an immuno-oncology company that focuses on developing first-in-class drugs with novel mechanisms.
2,662,782 bioAffinity Technologies (TX, USA) is a cancer diagnostics company that develops non-invasive, early-stage diagnostics to detect cancer and diseases.
2,805,964 Oncimmune (United Kingdom) is engaged in developing and commercializing its EarlyCDT platform technology.
3,000,000 CNS Pharmaceuticals, Inc. (TX, USA) is a pre-clinical stage biotechnology company specializing in the development of novel treatments for brain tumors.
3,000,000 Bionano (CA, USA) is a biotechnology company that provides genome analysis solutions to researchers and clinicians.
4,000,000 Bio-Path Holdings (TX, USA) is a biotechnology company developing therapeutic products for the liposomal delivery of nucleic acids in cancer patients.
4,000,000 Mustang Bio (NY, USA) is a clinical-stage biopharmaceutical company focused on translating today’s medical breakthroughs in cell and gene therapies into potential cures for hematologic cancers, solid tumors, and rare genetic diseases.
4,396,414 SAREUM HOLDINGS PLC (United Kingdom) is a drug discovery company that produces targeted small molecule therapeutics, focusing on cancer.
4,500,000 Shuttle Pharmaceuticals, Inc. (MD, USA) is a clinical-stage pharmaceutical company utilizing proprietary technology to develop novel therapies.
5,000,000 BriaCell Therapeutics Corp. (NY, USA) is an immuno-oncology focused biotechnology company developing targeted and effective approaches for the management of cancer.
5,000,000 Lexaria Bioscience (Canada) develops its DehydraTECH technology that promotes healthy administration methods.
5,000,000 iSpecimen (MA, USA) is the marketplace for human biospecimens, providing researchers with the samples they need from the patients they want.
5,000,000 Tiziana Life Sciences (United Kingdom) is a biotechnology company focused on transformational technology enabling alternative routes for immunotherapy.
6,500,000 Applied DNA Sciences (NY, USA) provides botanical DNA-based anti-counterfeiting and product authentication solutions.
6,664,500 BioVie Inc. (MA, USA) is a clinical-stage biopharmaceutical company developing drug therapies to treat neurological and neurodegenerative disorders, and advanced liver disease.
7,200,000 NLS Pharmaceutics AG (Switzerland) is a clinical-stage drug development company focusing on neurobehavioral and neurocognitive disorders and their pharmacognosia.
7,584,257 Sirnaomics Ltd. (MD, USA) is a biopharmaceutical company developing therapeutics for critical human diseases by using RNA interference technology.
10,000,000 Coya Therapeutics, Inc. (TX, USA) is a T Reg platform company addressing neurodegenerative, autoimmune, and metabolic diseases.
10,200,000 Oncocyte Corporation (CA, USA) is a biotech company helping save lives and improve outcomes by accelerating and optimizing the diagnosis and treatment of cancer.
10,200,000 CalciMedica (CA, USA) is engaged in the discovery and development of small molecule drugs for the treatment of inflammatory and autoimmune disorders.
12,100,000 Curis (MA, USA) is a drug development company committed to leveraging its innovative signaling pathway drug technologies to create new targeted small molecule drug candidates for cancer.
12,400,000 IN8bio (NY, USA) is a biotechnology company focused on delivering a novel off-the-shelf product for the treatment of cancer.
19,200,000 Monopar Therapeutics Inc. (IL, USA) is an emerging biopharmaceutical company focused on developing orphan oncology compounds.
20,000,000 Molecular Partners (Switzerland) is a clinical-stage biopharmaceutical company developing a powerful new class of potent, specific, and versatile small protein therapies called DARPin® therapeutics.
24,300,000 Lifecore Biomedical (MN, USA) is a full-service contract development and manufacturing organization (CDMO) partnering with pharmaceutical and biotech companies to develop and deliver vital and complex injectable therapies.
27,000,000 Onconetix (OH, USA) is a biotechnology company that focuses on research and development of universal flu vaccines.
30,000,000 Insighta Limited (Hong Kong) is an early cancer detection company that focuses on developing tests and clinical trials for additional cancer types.
31,977,822 Eupraxia Pharmaceuticals Inc. (Canada) is a clinical-stage biotech company developing locally delivered, extended-release alternatives to currently approved drugs.
35,000,000 Bright Minds Biosciences (Canada) is a biotech company developing serotonergic therapeutics to treat mental health disorders.
43,313,169 enGene (Canada) is a biotechnology company developing treatments for mucosal diseases through inducing therapeutic proteins of harmful proteins.
65,000,000 OnKure Therapeutics (CO, USA) is a clinical-stage biopharma company developing precision medicines targeting validated cancer drivers.
75,000,000 Capricor Therapeutics, Inc. (CA, USA) is a biotechnology company focusing on cell and exosome-based therapeutics.
75,000,000 ProQR Therapeutics (Netherlands) is a biotech company focused on developing drugs to treat genetic disorders.
85,000,000 Eledon Pharmaceuticals, Inc. (CA, USA) is a biotechnology company developing treatments for people undergoing organ or cellular transplantation.
102,693,943 Inventiva Pharma (France) is a biopharmaceutical company with several drug candidates at clinical and preclinical stage.
110,000,000 Inhibikase Therapeutics, Inc. (GA, USA) is a developer of cellular Abelson tyrosine kinase inhibitors to treat infections and other diseases.
150,000,000 Immatics (Germany) is a biopharmaceutical company focused on the development of immunotherapeutic substances for cancer therapy.
248,000,000 Harmony Biosciences (PA, USA) is a pharmaceutical company that develops and commercializes novel therapies for rare neurological disorders.
250,000,000 Akeso Biopharma (China) is a biopharmaceutical company committed to the discovery, development, and commercialization of therapies.
300,000,000 Scholar Rock (MA, USA) is a biopharmaceutical company that develops and discovers new medicines and treatments for serious diseases.
300,000,000 Vera Therapeutics, Inc. (CA, USA) is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential.
500,000,000 Crinetics Pharmaceuticals (CA, USA) is a clinical-stage pharmaceutical company that develops therapies for people with rare endocrine diseases.
1,000,000,000 PFIZER INC. (NY, USA) is a biopharmaceutical company that provides affordable access to safe, effective medicines and health care services.
November
186,204 Thiogenesis Therapeutics, Corp. (Canada) is a clinical-stage biotech company developing thiol-active therapeutics to treat medical diseases.
200,000 Ikonisys (CT, USA) is transforming diagnostic medicine by enabling early, accurate, and non-invasive disease detection.
709,927 BioVaxys Technology Corp. (NY, USA) is a clinical-stage biotechnology company developing immunotherapeutic cancer vaccines targeting melanoma.
774,840 Hemogenyx Pharmaceuticals (United Kingdom) is developing new treatments for blood diseases such as leukemia and lymphoma.
888,756 Rakovina Therapeutics (Canada) is a publicly traded company focused on developing new cancer treatments based on novel DNA-damage response technologies.
1,293,464 Attana (Sweden) develops third-generation biosensors used to determine specificity.
2,100,000 Cyclacel Pharmaceuticals, Inc. (NJ, USA) develops oral therapies to treat cancers and other critical diseases.
2,273,446 Circio Holding ASA (Norway) develops active immunotherapy in the form of cancer vaccines for post-operation treatments.
3,000,000 Intensity Therapeutics, Inc. (CT, USA) is a biopharmaceutical company providing chemotherapy treatment for cancer patients.
3,000,000 Citius Pharmaceuticals, Inc. (NJ, USA) is a biopharmaceutical company that develops and commercializes therapeutic products.
3,043,740 GenSight Biologics (France) develops gene therapy-based treatments for retinal degenerative diseases.
4,500,000 Qualigen Therapeutics (CA, USA) is a biotechnology company focused on developing and commercializing novel therapeutic products for cancer and infectious diseases, as well as expanding its FastPack® diagnostic platform.
4,700,000 Cadrenal Therapeutics, Inc. (Nasdaq: CVKD) (FL, USA) develops a late-stage novel therapy for patients with end-stage renal disease and atrial fibrillation.
5,000,000 Sonnet BioTherapeutics (NJ, USA) is a biotechnology company innovating biologic drugs with single or bispecific mechanisms of action.
5,701,051 Aptose Biosciences, Inc. (Canada) is a biopharmaceutical company focused on the discovery, research, and development of novel, first-in-class therapies.
5,916,556 SynAct Pharma (Sweden) develops drugs for acute deterioration in inflammatory diseases.
6,900,000 HCW Biologics (FL, USA) is developing immunotherapies to lengthen healthspan by disrupting the link between cellular senescence and disease.
7,000,000 BioXcel Therapeutics, Inc. (CT, USA) is a clinical-stage biopharmaceutical company focused on drug development that utilizes novel artificial intelligence.
7,500,000 Calidi Biotherapeutics (CA, USA) is a clinical-stage biotechnology company developing immunotherapies for cancer.
8,000,000 TransCode Therapeutics, Inc. (MA, USA) is an RNA oncology company that develops and commercializes drugs for the treatment of metastatic cancer.
8,199,999 Modular Medical, Inc. (CA, USA) operates as a drug delivery tech developer.
9,000,000 BioLineRx (Israel) is a late clinical-stage biopharmaceutical development company that focuses on oncology.
11,599,225 Ondine Biomedical Inc. (Canada) develops non-antibiotic, anti-infective therapies for a broad spectrum of bacterial, viral, and fungal infections.
28,750,000 Belite Bio (CA, USA) is a clinical-stage biopharmaceutical drug development company.
35,869,550 Alpha Cognition, Inc. (Canada) specializes in developing treatments for underserved neurodegenerative diseases.
44,000,000 Lomond Therapeutics (CA, USA) creates pharmacological platforms that target escape mutations.
66,000,000 Lineage Cell Therapeutics (CA, USA) is a clinical-stage biotechnology company developing novel cellular therapies to treat unmet medical needs.
69,400,000 Avalo Therapeutics (MD, USA) is a leading clinical-stage biopharmaceutical company that employs a precision medicine approach to discover, develop, and commercialize targeted therapeutics for patients with significant unmet clinical needs.
80,000,000 Aclaris Therapeutics, Inc. (PA, USA) is a specialty pharmaceutical company engaged in developing dermatologic therapies.
105,000,000 Cidara Therapeutics (CA, USA) is a biotechnology company that specializes in the fields of healthcare and therapeutics.
125,000,000 Travere Therapeutics (CA, USA) discovers and develops drugs for the treatment of catastrophic diseases that are debilitating and often life-threatening.
125,000,000 89bio (CA, USA) is a biopharmaceutical company building a pipeline of biologic and small molecule treatments for liver and metabolic disorders.
140,000,000 Replimune (MA, USA) develops the next generation of oncolytic immunotherapies for the treatment of cancer.
200,000,000 Spyre Therapeutics (CA, USA) is a biotechnology business that is developing a strong pipeline of antibody therapies.
200,000,000 Zai Lab (China) brings transformative medicines for cancer, autoimmune, and infectious diseases to patients in China and around the world.
200,000,000 Neurogene Inc. (NY, USA) is a developer of genetic medicines intended to improve patient outcomes for neurological disorders.
325,000,000 Arrowhead Pharmaceuticals (CA, USA) is a biotechnology company that focuses on the development of medicine to treat diseases with a genetic origin.
Unknown Silexion Therapeutics Corp (IL, USA) is a biotechnology company that provides research and development for oncology treatments.
December
175,000 BioVaxys Technology Corp. (NY, USA) develops immunotherapeutic cancer vaccines targeting melanoma.
223,665 RepliCel Life Sciences Inc. (Canada) is a regenerative medicine company using cell therapy products for healing tendinosis, aging, and pattern baldness.
250,000 Moss Genomics (Canada) leverages Artificial Intelligence, DNA, microbiome, and epigenetic data for alternative health solutions.
480,000 Phio Pharmaceuticals Corp. (MA, USA) specializes in the application of RNAi therapies in immuno-oncology.
486,990 InnoCan Pharma (Israel) develops novel therapeutics platforms and products to improve quality of life.
500,000 NLS Pharma (Switzerland) focuses on neurobehavioral and neurocognitive disorders and their pharmacognosia.
950,000 MAIA Biotechnology, Inc. (IL, USA) focuses on developing first-in-class drugs with novel mechanisms in immuno-oncology.
1,000,000 Telomir Pharmaceuticals, Inc. (MD, USA) develops a novel treatment that binds critical metals to interrupt enzyme function.
1,560,674 GenSight Biologics (France) develops gene therapy-based treatments for retinal degenerative diseases.
1,561,719 PharmAla Biotech Inc. (MDMA.CSE) (Canada) provides manufacturing and sales of MDMA substances to the clinical research community.
1,722,000 Lipella Pharmaceuticals ( PA, USA) develops products for intravesical therapy.
1,790,750 Telo Genomics (Canada) offers a telomere platform for biopsies and related technologies in oncology and neurological diseases.
1,900,000 Eyenovia, Inc. (NY, USA) provides a portfolio of next-generation topical eye treatments.
1,900,000 Volition (NV, USA) develops easy-to-use blood-based cancer tests to accurately diagnose a range of cancers.
1,935,112 Cambium Bio (Australia) focuses on the development and commercialization of regenerative therapies derived from novel processed human platelets.
2,020,000 Tharimmune, Inc. (United Kingdom) is a development-stage company advancing improved therapies for patients with cancer.
2,132,890 Kane Biotech Inc. (Canada) engages in the research and development of products to prevent and disperse biofilms.
2,705,118 TME Pharma ( Germany) develops biostable aptamers and substances based on mirror image nucleic acids.
2,800,000 Purple Biotech (Israel) is an innovative biopharmaceutical drug development company.
2,900,000 180 Life Sciences (CA, USA) develops novel drugs for treating distinct inflammatory diseases.
2,918,162 Defence Therapeutics (Canada) uncovers enhanced treatment solutions for future generations.
3,400,000 Palatin Technologies (NJ, USA) develops targeted receptor-specific peptide therapeutics to treat diseases.
3,900,000 Sonnet BioTherapeutics (NJ, USA) innovates biologic drugs with single or bispecific mechanisms of action.
4,000,000 Revelation Biosciences Inc. (CA, USA) develops immunologic therapeutics and diagnostics designed to make the world a healthier place.
5,000,000 CEL-SCI Corporation (VA, USA) develops immunotherapy products for the treatment of cancer and other infectious diseases.
5,000,000 Palisade Bio (CA, USA) is a clinical-stage biopharmaceutical company that develops therapies for acute and chronic gastrointestinal complications.
5,000,000 Serina Therapeutics, Inc. (AL, USA) employs its proprietary polymer technology to develop treatments for cancer, inflammation, pain, and metabolic disorders.
5,000,000 NeuroSense Therapeutics (Israel) is a clinical-stage drug development company advancing a groundbreaking treatment for ALS.
5,500,000 BriaCell Therapeutics Corp. (NY, USA) is an immuno-oncology focused biotechnology company developing targeted and effective approaches for the management of cancer.
5,830,663 Phase Holographic Imaging (Sweden) provides time-lapse cytometers for cancer and stem cell researchers in Europe, Asia, and North America.
6,000,000 OS Therapies (MD, USA) is a therapeutics company focused on the identification, development, and commercialization of treatments for osteosarcoma.
6,200,000 Aptevo Therapeutics Inc (WA, USA) is a biotech company primarily focused on bringing novel oncology and hematology therapeutics to market.
6,800,000 Quoin Pharmaceuticals (VA, USA) is focused on developing products that address major unmet medical needs.
7,900,000 Innate Pharma (France) is a biopharmaceutical company developing immunotherapy drug candidates for the treatment of cancer and inflammatory diseases.
8,000,000 Mainz Biomed (Germany) is a molecular genetic diagnostics company developing market-ready molecular genetic diagnostic solutions.
8,100,000 ProQR Therapeutics (Netherlands) is a biotech company focused on the development of drugs to treat genetic disorders.
8,970,509 Lytix Biopharma (Norway) is a pharmaceutical company specializing in anti-microbials and cancer therapeutics.
9,200,000 BioAtla, Inc. (CA, USA) develops safer, more effective drugs for cancer using a proprietary next-generation antibody discovery and evolution platform.
10,239,115 Paradigm Biopharmaceuticals (Melbourne, Australia) is a global biopharmaceutical company driven to discover and improve patients’ health and quality of life.
10,750,000 KALA BIO (MA, USA) develops novel treatments for diseases that affect mucosal tissues.
11,856,846 Avantium (Netherlands) provides high-throughput R&D technologies for applications in the energy, chemicals, and pharmaceutical industries.
13,126,320 Scancell (United Kingdom) is focused on developing innovative immunotherapies for cancer that stimulate the body’s immune system.
14,500,000 PolyPid Ltd. (Israel) offers a technology platform enabling controlled and prolonged release of active pharmaceutical ingredients (API).
16,100,000 Marker Therapeutics, Inc. (MN, USA) is a clinical-stage developer of a transformative, non-genetically engineered, multi-antigen T cell therapy platform.
16,300,000 Delcath Systems (NY, USA) is an interventional oncology company focusing on the treatment of metastatic liver cancer.
20,000,000 Traws Pharma, Inc (PA, USA) is a clinical-stage biopharmaceutical business focused on creating best-in-class small molecule oral therapies for respiratory diseases.
25,000,000 FibroBiologics (Nasdaq: FBLG) (TX, USA) is a regenerative medicine company developing an innovative solution for chronic disease treatment using fibroblast cells.
27,600,000 Inotiv (IN, USA) provides biopharmaceutical analytical, reproductive toxicology, medical device testing, DMPK, consulting, and pathological services.
30,000,000 Assembly Biosciences, Inc. (IN, USA) is a public biotechnology company and provider of oral biologic therapeutics.
30,000,000 INOVIO Pharmaceuticals, Inc. (PA, USA) is a biotech company focusing on bringing to market DNA medicines for diseases associated with HPV, cancer, and infectious diseases.
40,000,000 Cardiff Oncology (CA, USA) develops drugs that target cell division for the treatment of leukemias, lymphomas, and solid tumor cancers.
40,000,000 Monopar Therapeutics Inc. (IL, USA) is an emerging biopharmaceutical company focused on developing orphan oncology compounds.
42,242,429 Foresee Pharmaceuticals (Taiwan) is a clinical-stage pharmaceutical company.
50,000,000 Personalis, Inc. (CA, USA) is a contract research organization and genome-scale diagnostics services company specializing in genome-guided medicine.
50,000,000 Trevi Therapeutics, Inc. (CT, USA) is a clinical-stage biopharmaceutical company developing drugs for treating uremic pruritus.
55,600,000 Vor Bio (MA, USA) is an immuno-oncology company developing therapies for treating cancer.
75,000,000 Ikena Oncology (MA, USA) develops differentiated therapies to target cancer growth and resistance, focusing on Hippo and RAS signaling pathways.
79,000,000 Precigen (MD, USA) is a life sciences company researching and developing bio-therapeutic control systems to minimize toxicity.
92,000,000 Candel Therapeutics (MA, USA) develops cancer immunotherapies designed to improve the lives of cancer patients and their families.
100,000,000 Aadi Bioscience, Inc (CA, USA) develops a potentially mTOR inhibitor for targeted patient populations in oncology and cardiovascular diseases.
100,000,000 Protara Therapeutics (NY, USA) develops transformative therapies for people with cancer and rare diseases with limited treatment options.
100,000,000 ImmunityBio, Inc. (CA, USA) is a late-stage immunotherapy startup developing treatments to drive immunogenic pathways in the fight against cancer.
150,000,000 RAPT Therapeutics (CA, USA) is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer.
238,000,000 CG Oncology (CA, USA) is a clinical-stage biopharmaceutical company focused on developing oncolytic immunotherapies to combat cancer.
250,000,000 Olema Oncology (CA, USA) is a preclinical biotechnology company developing new drugs for the treatment and prevention of breast cancer.
350,000,000 Janux Therapeutics (CA, USA) develops immunotherapies that generate immune responses to prevent tumors without affecting a patient’s healthy tissue.
452,600,000 NewAmsterdam Pharma Corporation (Noord-Holland, Netherlands) is a clinical-stage company focused on the research and development of transformative therapies for cardio-metabolic diseases.
750,000,000 Revolution Medicines (CA, USA) is developing new therapies through an innovative approach that harnesses the complex chemicals of life by reconfiguring natural substances into best-in-class medicines.
Post-IPO Debt
October
660,071 Phase Holographic Imaging (Sweden) provides time-lapse cytometers for cancer and stem cell researchers in Europe, Asia, and North America.
2,833,668 Medivir AB (Sweden) is a research-based pharmaceutical company focused on oncology and infectious diseases.
1,500,000,000 Endo Pharmaceuticals (Ireland) is a global specialty pharmaceutical company focused on improving patients’ lives while creating value.
November
444,309 Marinomed Biotech AG (Austria) is a biopharmaceutical company that develops innovative anti-viral and immunological treatments.
457,708 Modus Therapeutics Holding AB (Sweden) is a Swedish drug development company focused on normalizing the lives of patients with Sickle Cell Disease.
1,049,637 Defence Therapeutics (Canada) is a scientific pioneer on a journey to uncover enhanced treatment solutions for future generations.
3,500,000 Gilead Sciences (CA, USA) is a biopharmaceutical company that discovers, develops, manufactures, and commercializes therapies for critical diseases.
20,000,000 Agenus (MA, USA) develops and commercializes immunotherapies and vaccines for cancer and infectious diseases.
30,000,000 Ocugen (PA, USA) is a biotechnology company that develops novel gene and cell therapies to improve health and patient outcomes.
50,000,000 Alector (CA, USA) is combining state-of-the-art antibody technology and recent discoveries in neuroimmunology and human genetics to develop novel treatments.
179,000,000 KalVista Pharmaceuticals, Inc. (MA, USA) is an ophthalmology company focused on developing drugs for the treatment of diabetic macular edema (DME).
200,000,000 Disc Medicine (MA, USA) is a biopharmaceutical company that develops therapies for hematologic diseases and rare blood disorders.
250,000,000 Geron Corporation (CA, USA) is a biotechnology company that specializes in developing blood cancer treatments for hematologic malignancies.
400,000,000 Indivior (VA, USA) is a global pharmaceutical company working to help change patients’ lives by developing medicines to treat substance use disorder and serious mental illnesses.
631,600,000 DRI Healthcare (Canada) provides unitholders with differentiated exposure to the anticipated growth in the global pharmaceuticals and biotechnology markets.
692,070,259 XtalPi Inc. (MA, USA) is a pharmaceutical technology company that is reinventing drug discovery by enabling dry lab predictions with wet lab validation.
December
1,819,787 Xbrane Biopharma AB (Sweden) develops novel technologies for bacterial protein expression.
5,000,000 Cingulate Therapeutics (NJ, USA) uses a unique combination of delivery technology and proven medications to create an unmatched release profile.
5,000,000 Northwest Biotherapeutics (MD, USA) is a biotechnology company focused on developing and commercializing immunotherapy products to treat cancer.
5,265,652 Cellectis (France) is a biopharmaceutical company that develops adoptive immunotherapies for cancer.
11,250,000 Danimer Scientific (GA, USA) is a biotechnology company that makes bioplastics used in disposable container coatings, packaging, and other products.
22,000,000 Lucid Diagnostics (NY, USA) develops a non-invasive, office-based diagnostic test for biomarkers to detect esophageal cancer.
30,000,000 Chimerix, Inc. (NC, USA) is a biotechnology company developing therapeutics for antiviral diseases.
50,000,000 Soleno Therapeutics, Inc. (CA, USA) is researching and developing medicines to treat rare genetic disorders, beginning with Prader-Willi syndrome (PWS).
52,500,000 TScan Therapeutics (MA, USA) is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer.
59,981,119 IO Biotech (Denmark) is a clinical-stage biotech company developing disruptive immune therapies for the treatment of cancer.
75,000,000 Theratechnologies Inc. (Canada) is a biopharmaceutical company engaged in the discovery of therapeutic products for commercialization.
193,700,000 MannKind Corporation (CA, USA) focuses on the discovery and development of therapeutic products for patients with diseases such as diabetes.
210,000,000 Esperion (MI, USA) discovers and develops pharmaceutical products for the treatment of cardiovascular and metabolic diseases.
5,287,810,223 Bayer (Germany) is a life science company that specializes in the areas of health care and agriculture.
Debt financing
October
21,863,276 LUMICKS (The Netherlands) provides single-molecule analysis technologies for cancer research and immunotherapy.
November
2,512,228 Ingenza Ltd (United Kingdom) is a dynamic CRDMO that leverages its engineering biology expertise to accelerate clients’ paths to commercial success.
524,146,925 Grünenthal Group (Germany) is a pharmaceutical company focused on R&D and treatments for pain management and related diseases.
December
566,073 Limula (Switzerland) offers a modular and automated solution for on-demand and at-scale manufacturing of cell therapies.
839,578 BiPER Therapeutics (France) is a biotech company developing and commercializing novel therapeutics.
2,650,000 TIXiMED (AL, USA) is a biotechnology company that develops and commercializes medicines for diabetes treatment.
7,358,832 Astraveus (France) is developing the next generation of cell and gene therapy (CGT) manufacturing solutions.
15,000,000 Nature’s Toolbox, Inc. (NTx) (NM, USA) is a biotechnology company providing a proprietary host-independent biological manufacturing and development platform.
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